Kisspeptin-10 (5MG)

Kisspeptin-10 (KP-10) – 10-Amino Acid Research Peptide | Prax Peptides

Manufacturer: Prax Peptides
Purity: ≥99%
Form: Lyophilized Peptide (Sterile Vial)
Molecular Formula: C₆₃H₈₃N₁₇O₁₄
Molecular Weight: 1302.4 g/mol
CAS Number: 374675-21-5
Synonyms: Kisspeptin-10, KP-10, Kisspeptin-10 (Human), Metastin (45-54)

Overview

Kisspeptin-10 (KP-10) is the shortest biologically active fragment of the kisspeptin peptide family, encoded by the KISS1 gene. It is a potent natural ligand for the KISS1R (GPR54) receptor—an essential regulator of reproductive and neuroendocrine function.

By stimulating gonadotropin-releasing hormone (GnRH), Kisspeptin-10 triggers the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which play key roles in testosterone production, fertility, and reproductive health.

Ongoing studies suggest that Kisspeptin-10 may also influence sexual behavior, appetite regulation, metabolic balance, and tumor suppression, making it a valuable peptide for a wide range of pre-clinical research applications.

Chemical Structure

• Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂

• Molecular Formula: C₆₃H₈₃N₁₇O₁₄

• Molecular Weight: ~1302.4 g/mol

• PubChem CID: 25240297

Research Applications

1. Reproductive Health & Hormone Regulation

• Stimulates GnRH release, increasing LH and FSH secretion.

• Enhances testosterone production in males.

• Investigated for use in infertility, hypogonadism, and reproductive aging research.

2. Sexual Behavior & Motivation

• Shown in animal studies to increase sexual activity and copulation frequency.

• Human trials demonstrate enhanced sexual brain response and arousal during stimuli.

• Potential relevance for studying hypoactive sexual desire disorder (HSDD).

3. Cancer Biology

• Displays anti-metastatic activity in multiple cancer types, including cervical, colon, lung, and brain cancers.

• Research suggests KP-10 analogs may inhibit tumor cell migration and proliferation via kinase pathway modulation.

4. Cardiovascular Research

• Regulates mTOR and AKT pathways, potentially reducing oxidative stress.

• May enhance collagen synthesis in cardiac tissue and influence heart remodeling.

• Low kisspeptin levels have been associated with ischemic heart disease.

5. Metabolism & Appetite Regulation

• Shown to suppress appetite and increase energy expenditure in animal models.

• Being studied for potential applications in obesity, metabolic disorders, and energy homeostasis.

Product Specifications

• Compound: Kisspeptin-10 (KP-10)

• Purity: ≥99% confirmed via HPLC and Mass Spectrometry

• Formulation: Lyophilized sterile peptide

• Storage:

  • Store powder refrigerated at 2°C–8°C or colder.

  • After reconstitution with bacteriostatic water, store cold and use within 30 days.

Why Choose Prax Peptides

Prax Peptides produces all research compounds in FDA-registered, cGMP-compliant U.S. laboratories. Each batch undergoes HPLC and MS analysis to verify 99%+ purity, providing reliable results for advanced pre-clinical and biochemical research.

Legal Disclaimer

This compound is for research use only. It is not approved for human consumption, medical treatment, or diagnostic use.
Handle with appropriate laboratory safety equipment.
Keep out of reach of children. Misuse may cause adverse effects.