What is PT-141 (10MG)?
PT-141, also known as Bremelanotide, is a synthetic research peptide derived from alpha-melanocyte-stimulating hormone (α-MSH).
It is being studied in laboratory and pre-clinical environments for its effects on melanocortin receptor activation, sexual behavior research, and neuroendocrine modulation.
Unlike compounds that influence vascular pathways, PT-141 interacts directly with central nervous system receptors—specifically MC-4R and MC-1R—to explore mechanisms related to sexual motivation, libido signaling, and neural response.
Current areas of research include:
Neuroactive peptide studies on arousal and behavioral response
Melanocortin receptor mapping and signal pathway analysis
Structure-function relationship studies in α-MSH derivatives
For laboratory research use only. Not for human consumption.
Structure of Chemicals – Prax Peptides
Chemical Structure of PT-141 (10MG)
PT-141 is a cyclic heptapeptide analog of Melanotan II, designed to selectively activate melanocortin receptors associated with neural and behavioral modulation.
Its conformationally stable structure enhances receptor affinity and resistance to enzymatic degradation, making it valuable for controlled peptide research.
Amino Acid Sequence:
AC-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
This molecular configuration enables efficient binding to MC-4R and MC-1R, allowing researchers to examine how melanocortin receptor signaling affects neurological and physiological responses.
Medical – Prax Peptides
What Are the Effects of PT-141 (10MG)?
Neuroendocrine Pathway Research
PT-141 is used in neuroscience and endocrinology research to study melanocortin receptor signaling and its impact on sexual motivation, neural excitation, and behavioral responses in animal models and in-vitro systems.
Melanocortin Receptor Activation
Studies have demonstrated PT-141’s ability to engage MC-4R and MC-1R receptors, enabling analysis of neurochemical communication and hormonal response pathways associated with central arousal mechanisms.
Immune Modulation Studies
Preliminary data indicate potential involvement of MC-1R activation in immune system regulation and inflammatory control, positioning PT-141 as a valuable research compound in immunological and cellular signaling exploration.
Pharmacological Stability
As a Melanotan II analog, PT-141 features enhanced receptor selectivity, prolonged stability, and reduced off-target effects, making it ideal for laboratory investigation of peptide-based neural modulators.
Disclaimer
All Prax Peptides compounds, including PT-141 (10MG), are sold for laboratory research use only.
They are not intended for human use, medical treatment, or diagnostic purposes.
This product is designed strictly for controlled research applications involving melanocortin receptor pharmacology, neurobehavioral pathways, and biochemical analysis.
Quality & Research Standards
Every Prax Peptides research compound is manufactured in a certified facility and independently verified by a third-party lab to meet or exceed 99% purity. Each batch ships with a Certificate of Analysis documenting identity, purity, and mass-spectrometry results. We ship the same business day for orders placed before our cutoff, with discreet packaging and temperature-protective materials for every order.
Helpful Research Tools
New to working with lyophilized peptides? Use our free Peptide Reconstitution Calculator to determine accurate reconstitution volumes and per-unit dosing for any research compound. Pair your order with bacteriostatic water or a reconstitution solution for proper handling. Explore the full catalog on our research peptides shop.
Further Reading
Want more context on where this compound fits in current peptide science? Read our latest article: The 3 Peptides Smart Researchers Are Watching.
Research Use Only. All products sold by Prax Peptides are intended exclusively for in-vitro laboratory research and are not for human or veterinary consumption, diagnostic use, or therapeutic application.
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