5-Amino-1MQ (50MG)

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a synthetic small-molecule research compound that acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT) — an enzyme central to nicotinamide and NAD⁺ metabolic pathways. By blocking NNMT activity, 5-Amino-1MQ preserves nicotinamide for NAD⁺ synthesis, which is a key cofactor in cellular energy production, redox reactions, and regulation of metabolic signaling cascades in preclinical and in-vitro studies.

NNMT is highly expressed in adipose tissue and is associated with metabolic dysregulation, increased fat storage, and lower cellular energy availability. In research settings, inhibition of NNMT is explored for its effects on metabolic regulation, NAD⁺ homeostasis, mitochondrial function, and related pathways.

Each capsule contains 50 mg of 5-Amino-1MQ.