5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme that regulates cellular energy metabolism and fat storage. Unlike most peptides, 5-Amino-1MQ does not require reconstitution with bacteriostatic water — but accurate dosing is still critical to research reproducibility.
For peptides in your research stack that do require reconstitution, our free peptide dosage calculator handles all the math instantly.
What Is 5-Amino-1MQ?
5-Amino-1MQ selectively inhibits NNMT, an enzyme highly expressed in adipose (fat) tissue. By inhibiting NNMT, 5-Amino-1MQ has been shown in preclinical studies to:
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Convert vial strength, water volume, and desired dose into precise syringe units. Works for BPC-157, TB-500, GHK-Cu, and all research peptides.
Try the Calculator →- Raise intracellular NAD+ levels in adipocytes
- Increase resting metabolic rate
- Reduce adipocyte differentiation and fat cell size
- Improve insulin sensitivity markers in diet-induced obesity models
5-Amino-1MQ Dosage in Research
In published rodent studies, 5-Amino-1MQ has been administered at 50mg/kg/day in drinking water (dissolved at 0.1mg/mL). This route of administration produces consistent plasma levels without injection stress artifacts.
Prax Peptides 5-Amino-1MQ is supplied as a water-soluble powder suitable for either oral or dissolved administration in research settings.
Combining 5-Amino-1MQ With Other Research Compounds
5-Amino-1MQ is frequently studied alongside peptides in metabolic research stacks. Common combinations in published literature include pairings with GLP-1 receptor agonists for additive metabolic effects. If you’re working with peptides alongside 5-Amino-1MQ, use the peptide dosage calculator to accurately dose each compound in your protocol.
Storage and Handling
- Store at 2–8°C, away from light and moisture
- Shelf stable for 24+ months when stored correctly
- Dissolves readily in water at room temperature
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⚠️ Research Use Only: All compounds referenced on this site are intended strictly for laboratory research purposes. They are not approved for human use or consumption by the FDA or any regulatory authority. This content is for informational purposes only and does not constitute medical advice.