MOTS-C Research Peptide (10mg)
Supplier: Prax Peptides
Purity: 99%+
Formulation: 10mg Lyophilized Powder in Sterile Vial
Molecular Formula: $\text{C}_{102}\text{H}_{157}\text{N}_{29}\text{O}_{28}$
Scientific Overview & Mechanism of Action
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide that is unique because it is one of the few functional peptides encoded by the mitochondrial genome, not the nuclear genome. It is a key player in mitochondrial communication with the rest of the cell, particularly in skeletal muscle.
The primary mechanism of action is related to its ability to modulate metabolic homeostasis. Research indicates that MOTS-C may increase glucose uptake and utilization in muscle cells, enhance insulin sensitivity, and promote fatty acid metabolism. By influencing cellular energy balance, MOTS-C is a valuable tool for researchers studying the intersection of aging, metabolism, and muscle function.
Key Research Applications and Pre-Clinical Findings
- Glucose Metabolism: Studies have demonstrated that MOTS-C can significantly improve glucose handling and insulin sensitivity, suggesting potential for research into Type 2 diabetes and metabolic dysfunction.
- Skeletal Muscle Function: Research explores its role in promoting mitochondrial health within muscle tissue, potentially leading to increased energy capacity and better resistance to metabolic stress.
- Aging Research: As mitochondrial function declines with age, MOTS-C is a central focus in gerontology research for its potential to support metabolic health markers associated with longevity.
- Fatty Acid Oxidation: Pre-clinical models show that MOTS-C may promote the breakdown of fats for energy, supporting research into its use as a tool for studying weight management and body composition.
Product Specifications
- Compound: MOTS-C
- Concentration: 10 milligrams (mg) per vial
- Quantity: 1 vial (lyophilized powder)
- Storage: The lyophilized powder should be stored refrigerated at $2^\circ\text{C}$ to $8^\circ\text{C}$ or colder for long-term stability. Once reconstituted with bacteriostatic water, it should be stored refrigerated and used within 30 days.

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